UDP-sugar pyrophosphorylase (BlUSP)

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Name UDP-sugar pyrophosphorylase;BIUSP
Product Code EN01019
E.C. 2.7.7.64
Product Description E. coli recombinant UDP-sugar pyrophosphorylase from Bifidobacterium longum
Unit Definition One unit is defined as the amount of enzyme that catalyzes the formation of 1 μmol of UDP-Gal from Gal-1-P and UTP per minute at 37 °C.

Description

UDP-sugar pyrophosphorylase (BlUSP)

Accepted Name
UTP-monosaccharide-1-phosphate uridylyltransferase.
Alternative Name(s)
UDP-sugar pyrophosphorylase.
USP.
Reaction catalysed
UTP + a monosaccharide 1-phosphate <=> diphosphate + UDP-monosaccharide
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
  • The reaction can occur in either direction and it has been postulated that MgUTP and Mg-diphosphate are the actual substrates.
  • Catalyzes the formation of UDP-Glc, UDP-Gal, UDP-GlcA, UDP-L-Ara and UDP-Xyl, showing broad substrate specificity toward monosaccharide 1-phosphates.
  • Mannose 1-phosphate, L-fucose 1-phosphate and glucose 6-phosphate are not substrates and UTP cannot be replaced by other nucleotide triphosphates.

Additional information

Pack

100 U, 20U, 5 U, Other