α1,2-fucosyltransferase

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Name α1,2-fucosyltransferase; α1,2FucT
Product Code EN01013
E.C. 2.4.1.69
Product Description E. coli recombinant α1,2-fucosyltransferase from Helicobacter mustelae
Unit Definition One unit is defined as the amount of enzyme that catalyzes the formation of 1μmol Fucα1,2Lac from GDP-Fuc and lactose per minute at 37 °C.

Description

α1,2-fucosyltransferase

Accepted Name
Type 1 galactoside alpha-(1,2)-fucosyltransferase.
Alternative Name(s)
Alpha-(1->2)-L-fucosyltransferase.
Alpha-2-fucosyltransferase.
Alpha-2-L-fucosyltransferase.
Beta-galactoside alpha-1->2 fucosyltransferase.
Blood group H alpha-2-fucosyltransferase.
Blood-group substance H-dependent fucosyltransferase.
Galactoside 2-alpha-L-fucosyltransferase.
Guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase.
Guanosine diphosphofucose-galactoside 2-L-fucosyltransferase.
Guanosine diphosphofucose- galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L- fucosyltransferase.
Guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase.
Guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase.
Secretor-type beta-galactoside alpha-1->2 fucosyltransferase.
Reaction catalysed
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R
Comment(s)
  • The enzyme acts on a glycoconjugates where the substituent group is a glycoprotein or glycosphingolipid.
  • The recognized moiety of the substrate is known as a type 1 histo- blood group antigen precursor disaccharide, and the action of the enzyme produces an H type 1 antigen.
  • The enzyme from the bacterium Helicobacter pylori cannot act on type 2 substrates (see EC 2.4.1.344).

Additional information

Pack

10 U, 1U, 5 U, Other